Microdroplet Digital PCR System

The Microdroplet Digital PCR System comprises three integrated components: the Drop Maker sample preparation instrument, the Chip Reader biochip analyzer, and matching universal reagents with consumables. The TD-2 platform features simplified operation with minimal manual intervention steps throughout the workflow. The entire reaction process occurs within closed spaces preventing PCR product contamination during droplet generation, amplification, and detection phases. The system supports rare mutation detection, copy number variation analysis, and relative gene expression quantification applications across oncology, genetic disease, and infectious disease research fields.

The Drop Maker generates uniform microdroplets partitioning sample mixtures into thousands of individual reaction chambers for digital quantification. The Chip Reader employs optical detection systems analyzing fluorescence signals from amplified droplets to determine absolute target copy numbers without standard curve requirements. Closed-system architecture eliminates aerosol cross-contamination risks common in conventional PCR workflows. Universal reagent compatibility enables protocol adaptation for diverse molecular targets without custom formulation development.

Cancer research laboratories use the Microdroplet Digital PCR System for detecting low-frequency tumor mutations in heterogeneous tissue samples and monitoring minimal residual disease. Prenatal diagnostic centers employ the platform for non-invasive fetal aneuploidy screening through maternal plasma DNA analysis. Infectious disease surveillance programs deploy the system for viral load quantification in epidemiological studies. Gene therapy manufacturing facilities utilize the equipment for accurate viral vector titer determination during production quality control. Agricultural biotechnology labs apply the technology for precise GMO content quantification in crop breeding programs.

Tactical Supply Pakistan supplies digital PCR platforms enabling absolute nucleic acid quantification through droplet partitioning technology without amplification efficiency calibration. The company provides systems delivering single-copy sensitivity for rare allele detection in complex biological matrices.

Does the system require thermal cycler integration?
The platform operates with standard thermal cyclers for amplification between droplet generation and detection steps. Closed consumables maintain contamination prevention throughout the temperature cycling process.