1. Resolution & imaging capability — e.g., what voxel size (for 3D CT) or µm resolution (for surface/fluorescence) is required by your application.

  2. Sample size / capacity — Ensure the microscope’s chamber fits your samples (size, weight). The Bruker for example takes up to ~500 mm length and 20 kg weight.

  3. Technology features — Phase‑contrast, high‑energy X‑ray source, large detectors, software for reconstruction/visualisation (especially for 3D) matter a lot.

  4. Footprint & installation — Even “benchtop” systems may require significant space, power, shielding/radiation compliance.

  5. Support, maintenance & cost of ownership — X‑ray systems need calibration, possibly special safety approvals, cost of service, parts etc.

  6. Budget & value for your use‑case — These are high‑end instruments—ensure the spec meets your actual need and you’re not overpaying for features you won’t utilise.

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